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To understand low-dosing, you gotta understand how the drug works, first.

8 weeks ago suffered a 1st metatarsal break on my left foot was in a boot for 5 weeks towards. Colchicine Inflammatory Bowel Disease However, the total number of adverse events (diarrhoea, vomiting or nausea) is greater in those who receive high-dose colchicine versus placebo (62/74 in the high-dose colchicine group versus 11/50 in the placebo group (RR 3.81, 95% CI 2.28 to 6.38), with a number needed to treat to harm (NNTH) of 2 (95% CI 2 to 5).

Common options include oral contraceptives and anti-androgen drugs.

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